- Your Challenges
- Offerings
- News & Events
- Knowledge Center
- About Us
- Diagnostics
CE Marked
For In Vitro Diagnostic Use
The Vysis ToTelVysion Probe Kit consists of 41 TelVysion probes, including various LSI and CEP probes (64 probes in total).
Instructions for Use View Probe Maps & Design View Ordering Information
The 41 TelVysion probes are specific to:
The probes in ToTelVysion are provided in 15 mixtures. All probes are direct labeled, providing bright signals with minimal background noise. By utilizing SpectrumOrange, SpectrumGreen, SpectrumAqua, and a combination of SpectrumOrange and SpectrumGreen (to yield a yellow signal), each probe within a mixture is labeled with a unique color.
Vysis TelVysion Probes
Telomeres are DNA-protein complexes that cap the ends of eukaryotic chromosomes. Every telomere contains 3 to 20 kb of tandem TTAGGG repeats. The telomere associated repeats (TAR), also known as the subtelomeric repeats, are immediately proximal to the TTAGGG repeats. They contain regions of shared homology between subsets of certain chromosomes. Each TelVysion targeted site is a unique, chromosome specific DNA located approximately 100 to 300 kb from the chromosome end.
Schematic Of The Make-Up Of Human Chromosome Telomeric Regions
In the context of constitutional chromosome analysis, the most distal region of unique DNA on a chromosome arm commonly is referred to as the "subtelomere." Subtelomeres are known to contain a high concentration of genes as compared to other chromosome regions. Yet, subtelomere abnormalities can be difficult, if not impossible, to detect by routine G-band analysis because subtelomeres stain negative (light). Diagram courtesy of C. Lese and D. Ledbetter, University of Chicago.
Links which take you out of Abbott worldwide websites are not under the control of Abbott, and Abbott is not responsible for the contents of any such site or any further links from such site. Abbott is providing these links to you only as a convenience, and the inclusion of any link does not imply endorsement of the linked site by Abbott. The website that you have requested also may not be optimised for your screen size.
Please be aware that the website you have requested is intended for the residents of a particular country or countries, as noted on that site. As a result, the site may contain information on pharmaceuticals, medical devices and other products or uses of those products that are not approved in other countries or regions.
Please be aware that the website you have requested is intended for the residents of a particular country or countries, as noted on that site. As a result, the site may contain information on pharmaceuticals, medical devices and other products or uses of those products that are not approved in other countries or regions.