Molecular
Molecular

Vysis CEP 8 SpectrumOrange DNA 探针试剂盒

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Vysis CEP 8 SpectrumOrange 模式图

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供体外诊断使用

Vysis CEP 8 SpectrumOrange DNA 探针试剂盒是对 &agr; 卫星（着丝粒）区域 (8p11.1-q11.1) 具有特异性的 SpectrumOrange 标记探针。

图标链接使用说明查看探针图谱和设计查看订购信息

描述
 

CEP 8 SpectrumOrange DNA 探针试剂盒可供体外诊断使用，并且可用作标准核型分析的辅助手段以便对从骨髓所得细胞中的 8 号染色体进行识别和计数。在多点临床试验中，与传统细胞遗传学分析相比，CEP 8 SpectrumOrange DNA 探针试剂盒用于间期分析的灵敏度为 96%，特异性为 98%。研究已发现 8 号染色体三体与髓系原始细胞危象和嗜碱性细胞增多症之间都有着密切的关联。8 号染色体三体在以下几种特定疾病中是常见的遗传畸变：

  • 慢性髓细胞性白血病 (CML)
  • 急性髓细胞性白血病 (AML)
  • 骨髓增生性疾病 (MPD)
  • 骨髓增生异常综合征 (MDS)
  • 其他未指定的血液疾病 (HDNOS)

CEP 8 SpectrumOrange DNA 探针试剂盒内容物

每个 CEP 8 SpectrumOrange DNA 探针试剂盒包含：

  • 在杂交缓冲液 (220 µL) 中预变性的针对着丝粒区域 8p11.1-q11.1 的 CEP 8 SpectrumOrange &agr; 卫星 DNA
  • NP-40（洗涤溶液清洁剂：1000 µL）
  • DAPI II 复染剂 (300 µL)
  • 20X 标准柠檬酸钠 (SSC) 盐（1 瓶，66 克）

CEP 8 SpectrumOrange DNA 探针试剂盒的对照玻片也单独出售。参见订购编号 07J21-001 和订购编号 07J21-002。

探针信息

订购信息

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