AneuVysion 多色 DNA 探针试剂盒

CE 标志

供体外诊断使用

AneuVysion 多色 DNA 探针试剂盒 (Vysis CEP 18/X/Y - alpha satellite / LSI 13/21) 采用应用于未培养或培养的羊水细胞的专利荧光原位杂交 (FISH) 技术,可在 24 小时内提供三染色体 13、18 和 21(唐氏综合征)和性染色体异倍体的检测。

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描述
 

三染色体 13、18 和 21(唐氏综合征)和性染色体异倍体总共占羊膜穿刺术时发现的所有异常的近三分之二,占活产婴儿中检测到的临床显著的染色体异常的 85-90%。对 29,000 多份羊水标本的 AneuVysion 检测结果的回顾表明:该检测对三染色体 13、18 和 21 以及 X 和 Y 染色体异倍体的检测准确率为 99.9%。

 

Aneuvysion 检测的益处

由于在实验室接收到羊膜穿刺样本后 24 小时内(而不是常规染色体分析的 7 - 22 天)可以迅速获得结果,患者仅需面对较短时间的不确定性,从而获得心理上的益处。预期的 AneuVysion 结果可以让患者感到宽慰,因为他们知道胎儿所面临的大多数染色体异常已经以非常高的准确度被排除。重要的是,根据专业标准,获得的 AneuVysion 结果以及一致临床信息(即通过超声检查到的胎儿异常)可支持因妊娠晚期而不可用妊娠管理选项。最后,在罕见的培养失败的情况下,当不能获得标准细胞遗传学结果时,可以获得有关最可能异倍体的染色体数目信息。

 

AneuVysion 试剂盒内容物

每个 AneuVysion 试剂盒包括:

  • 两份探针混合物,总共五个 FISH 探针 
  • 洗涤试剂
  • DAPI 复染
  • 包含详细方案信息的试剂盒说明书

混合物 #1 和混合物 #2 由杂交缓冲液中标记探针和未标记的封闭 DNA 组成。

探针信息

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